3H-Imidazo[4,5-b]pyridin-7-amine

3H-Imidazo[4,5-b]pyridin-7-amine - Names and Identifiers

Name	1H-Imidazo[4,5-b]pyridin-7-amine
Synonyms	112698 1-Deazaadenine 7-Aminoimidazo[4,5-b]pyridine 3H-IMidazo[4,5-b]pyridin-7-aMine 3H-Imidazo[4,5-b]pyridin-7-amine 1H-Imidazo[4,5-b]pyridin-7-amine
CAS	6703-44-2

3H-Imidazo[4,5-b]pyridin-7-amine - Physico-chemical Properties

Molecular Formula	C6H6N4
Molar Mass	134.14
Density	1.61±0.1 g/cm3(Predicted)
Melting Point	257-259 °C(Solv: methanol (67-56-1); acetonitrile (75-05-8))
Boling Point	199.5±50.0 °C(Predicted)
pKa	9.05±0.20(Predicted)
Storage Condition	Room Temprature

3H-Imidazo[4,5-b]pyridin-7-amine - Introduction

1H-Imidazo[4,5-b]pyridin-7-amine, also known as 1H-Imidazo[4,5-b]pyridin-7-amine, is an organic compound. Its structure contains imidazole ring and pyridine ring, with a certain degree of aromaticity. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: A white to off-white crystalline powder.
-Solubility: In common organic solvents, such as ethanol and dimethyl sulfoxide, good solubility.
-Melting point: about 190-195°C.

Use:
- 1H-Imidazo[4,5-b]pyridin-7-amine is commonly used in medicinal chemistry research and in the pharmaceutical field.
-It can be used as an organic synthesis intermediate for the synthesis of other biologically active molecules.

Preparation Method:
- 1H-Imidazo[4,5-b]pyridin-7-amine is prepared by various methods, one of which is commonly used by the reaction of imidazole and 2-aminopyridine. In a specific process, imidazole may be first reacted with a base to generate sodium imidazole, and then 2-aminopyridine is added to react to obtain the target product.

Safety Information:
- 1H-Imidazo[4,5-b]pyridin-7-amine has not been included in international or national toxicity and risk assessment lists.
-During handling and use, good laboratory practices need to be observed to avoid direct contact with skin, eyes and inhalation.
-In case of contact, rinse immediately with plenty of water and seek medical help.

Please note that the above information is for reference only and does not represent all the properties and safety information of the compound. Relevant professional literature and local regulatory requirements are required for specific use and handling. In the laboratory or industrial production, it is important to follow strict safety procedures.

Last Update：2024-04-09 15:17:59